Unveiling the Properties of n-Butyl Phosphate: A Chemical Reagent


Release time:

2024-01-15

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Table of Contents: 1. Introduction: What is n-Butyl Phosphate? 2. The Composition and Structure of n-Butyl Phosphate 3. Physical Properties of n-Butyl Phosphate 4. Chemical Properties and Reactivity 5. Applications of n-Butyl Phosphate in Various Industries 6. Safety Precautions and Handling Guidelines 7. Frequently Asked Questions (FAQs) about n-Butyl Phosphate 8. Conclusion 1. Introduction: What

Unveiling the Properties of n-Butyl Phosphate: A Chemical Reagent
Table of Contents:
1. Introduction: What is n-Butyl Phosphate?
2. The Composition and Structure of n-Butyl Phosphate
3. Physical Properties of n-Butyl Phosphate
4. Chemical Properties and Reactivity
5. Applications of n-Butyl Phosphate in Various Industries
6. Safety Precautions and Handling Guidelines
7. Frequently Asked Questions (FAQs) about n-Butyl Phosphate
8. Conclusion

1. Introduction: What is n-Butyl Phosphate?


n-Butyl Phosphate, also known as butyl phosphate or butyl hydrogen phosphate, is a chemical compound widely used as a reagent in various industries. It belongs to the class of phosphate esters and is derived from the reaction between n-butanol and phosphoric acid. This versatile compound offers a range of properties that make it valuable in numerous applications, from manufacturing to research and development.

2. The Composition and Structure of n-Butyl Phosphate


n-Butyl Phosphate has a molecular formula of C4H11O4P and a molar mass of 150.09 g/mol. It consists of a butyl group (C4H9), a phosphate group (PO4), and a hydrogen atom (H). The butyl group provides the compound with its organic properties, while the phosphate group contributes to its reactivity and ability to form bonds with other substances.
The structure of n-Butyl Phosphate features a central phosphorus atom bonded to four oxygen atoms, one of which is doubly bonded. The other three oxygen atoms are attached to the butyl group, creating a stable and versatile compound.

3. Physical Properties of n-Butyl Phosphate


n-Butyl Phosphate is a colorless to pale yellow liquid with a characteristic odor. It has a relatively high boiling point of around 240°C (464°F) and a melting point of approximately -60°C (-76°F). The compound is slightly soluble in water but exhibits good solubility in organic solvents such as ethanol and acetone.

4. Chemical Properties and Reactivity


n-Butyl Phosphate displays various chemical properties that make it a valuable reagent in different chemical reactions. It acts as both a nucleophile and a Lewis base, allowing it to react with electrophiles and Lewis acids. The phosphate group can undergo hydrolysis under specific conditions, leading to the formation of phosphoric acid and butanol.
Additionally, n-Butyl Phosphate can form complexes with metals, enabling it to function as a chelating agent. This property finds applications in analytical chemistry, where it is utilized to separate and quantify metal ions present in complex mixtures.

5. Applications of n-Butyl Phosphate in Various Industries


n-Butyl Phosphate finds extensive use in diverse industries due to its unique properties. Some notable applications include:
- Pharmaceutical Industry: n-Butyl Phosphate acts as a solvent, extractant, and catalyst in the synthesis of various pharmaceutical compounds. Its ability to form complexes with metal ions helps in the separation and purification of drug substances.
- Agrochemical Industry: The compound is utilized as an intermediate in the production of herbicides, pesticides, and fungicides. It enhances the efficiency and stability of these agricultural chemicals, leading to improved crop yields and pest control.
- Petrochemical Industry: n-Butyl Phosphate serves as an essential component in the extraction and refining of petroleum products. It aids in separating impurities and improving the quality of fuels and lubricants.
- Research and Development: Due to its versatile reactivity, n-Butyl Phosphate is widely used in laboratories for various experiments and studies. It is also employed in the synthesis of organic compounds and as an analytical reagent.

6. Safety Precautions and Handling Guidelines


When working with n-Butyl Phosphate, it is crucial to follow safety precautions to minimize potential risks. Some guidelines to consider include:
- Wear appropriate personal protective equipment (PPE), such as gloves, goggles, and lab coats, to protect against skin and eye contact.
- Work in a well-ventilated area or under a fume hood to prevent inhalation of vapors.
- Avoid ingestion and keep the compound away from food, drinks, and smoking materials.
- Store n-Butyl Phosphate in a cool, dry place, away from heat and direct sunlight.
- Dispose of unused or waste material according to relevant regulations and guidelines.

7. Frequently Asked Questions (FAQs) about n-Butyl Phosphate


FAQ 1: What are the main properties of n-Butyl Phosphate?


n-Butyl Phosphate exhibits properties such as being a colorless to pale yellow liquid, having a characteristic odor, and being slightly soluble in water.

FAQ 2: How is n-Butyl Phosphate used in the pharmaceutical industry?


n-Butyl Phosphate is utilized as a solvent, extractant, and catalyst in the synthesis of various pharmaceutical compounds. It helps in the separation and purification of drug substances.

FAQ 3: Can n-Butyl Phosphate be used in agriculture?


Yes, n-Butyl Phosphate is used in the agrochemical industry as an intermediate in the production of herbicides, pesticides, and fungicides. It enhances the efficiency and stability of these agricultural chemicals.

FAQ 4: Is n-Butyl Phosphate hazardous to health?


n-Butyl Phosphate should be handled with care, following appropriate safety precautions. Direct contact with the compound may irritate the skin, eyes, and respiratory system. It is important to use PPE and work in well-ventilated areas.

FAQ 5: Can n-Butyl Phosphate be stored for a long time?


n-Butyl Phosphate should be stored in a cool, dry place, away from heat and direct sunlight. Following proper storage conditions, it can be stored for an extended period.

8. Conclusion


In conclusion, n-Butyl Phosphate is a valuable chemical reagent with diverse applications in various industries. Its unique properties, including reactivity, solubility, and complex formation, make it an essential component in pharmaceutical synthesis, agrochemical production, petrochemical refining, and research activities. By understanding the properties and applications of n-Butyl Phosphate, industries can utilize this versatile compound to enhance their processes, improve product quality, and drive innovation. Proper handling and adherence to safety guidelines are crucial to ensure its safe and effective utilization.